Keywords: 
• 仿生 /
• 微流控 /
• 智能 /
• 抗污染

Abstract: Biomimetic microfluidic systemscan be obtained through multidisciplinary approaches by using bio-inspired struc-tural and functional designsfor the microfluidic devices. This review mainly focuseson the concept of biomimetic microflu-idics to improve the properties of microfluidic systemsfor breaking through the bottlenecks of the current microfluidic devices, such as antifoulingsmart, anddynamic response insidethe microchannelsunder different environments. In addi-tion, here we show the current research progress of biomimetic microfluidic systems in applications related to antifouling and smart devices, and biomedical research. The review discusses both physical theories and critical technologies in the biomimetic microfluidics, from biomimetic design to real-world applications, so as to offer new ideas for the design and application of smart microfluidics, and the authors hope this review will inspire the active interest of many scientists in the area of the development and application of soft matter, and multi-functional and smart biomimetic devices.