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分布式电流刺激抑制心肌组织中螺旋波
Suppression of the spiral wave in cardiac tissue by using forcing currents with diversity?
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摘要: 利用两种恒定电信号刺激介质不同区域来产生分布式电流,外界分布式电流内化为跨膜电流后在介质中形成稳定的梯度力可抑制螺旋波的传播.当螺旋波被消除后系统进一步演化为均匀态且对应的膜片电位采样序列逐渐趋于一个稳定值.在考虑噪声情况下,该方法仍然能消除螺旋波,对其采样序列分析也验证了方法的可靠性.Abstract: @@@@Forcing currents are generated by using two types of constant currents to stimulate different areas of a medium. The external current is mapped into transmembrane current and stable gradient force is induced to drive the stable rotating spiral wave. The medium becomes homogeneous when the spiral wave is removed and the time series of sampled membrane potentials becomes stable value without considering noise. The scheme is confirmed to be effective in the presence of Gaussian white noise.
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